Clostridium difficile Infection Journal Articles

• Factors Associated With the Outcome of FMT for C. Difficile What factors might impact the variation in effectiveness of fecal microbiota transplantation in patients with recurrent C. difficile infection?
  Alimentary Pharmacology & Therapeutics, September 05, 2023
• Medical Therapies for Treatment and Prevention of Pouchitis This review assessed the efficacy of medical therapies including antibiotics, probiotics, biologics, and fecal transplantation for the treatment and prevention of pouchitis following colectomy for UC.
  Alimentary Pharmacology & Therapeutics, August 10, 2023
• Biologics After Exposure to TNF Inhibitors in Ulcerative Colitis This study assessed the real-world efficacy of vedolizumab, ustekinumab and tofacitinib as second-line therapies in patients with ulcerative colitis who were previously exposed to a TNF inhibitor.
  Alimentary Pharmacology & Therapeutics, August 08, 2023
• Diagnostic Stewardship: What Impacts Antibiotics Use? A better understanding of how diagnostic stewardship can impact antibiotic prescribing practices could help decrease unnecessary antibiotic use.
  Current Opinion in Infectious Diseases, August 03, 2023
• Misdiagnosis of C diff by Specimen Collection and Testing A new report finds that a number of inpatient C diff infections were not properly identified using standard-of-care specimen collecting and testing practices.
  Emerging Infectious Diseases, July 13, 2023
• Effectiveness of Exclusive Enteral Nutrition in Crohn's Disease This study aimed to elucidate the mechanisms of action in exclusive enteral nutrition in Crohn's disease. How does it promote anti-inflammatory and intestinal healing effects?
  Alimentary Pharmacology & Therapeutics, May 16, 2023
• Fecal Microbiota Transplantation for Recurrent C. Diff This paper identifies key challenges and improvement opportunities for the use of fecal microbiota transplantation for recurrent C. diff infections.
  Alimentary Pharmacology & Therapeutics, March 07, 2023
• Fecal Bile Acid to Predict Recurrence in C. Difficile Infection This study investigated how gut microbiota-bile acid interactions relate to the pathogenesis of C. difficile infection. Could fecal bile acids have potential as biomarkers to predict CDI recurrence?
  Alimentary Pharmacology & Therapeutics, December 28, 2022
• Advances in the Gut Microbiome and Mood Disorders This review summarizes recent advances in our understanding of the role of the gut microbiome in mood disorders, including the use of psychobiotics for the treatment and prevention of these disorders.
  Current Opinion in Psychiatry, December 21, 2022
• Characterization of C difficile Infections Among Adults How do the characteristics of adult patients with healthcare-associated C. difficile compare to those with community-associated infections?
  Emerging Infectious Diseases, July 07, 2022
• Intraoperative Redosing of Antibiotic for SSI Prevention When it comes to the administration of antibiotics to prevent surgical site infections, should additional intraoperative redosing be considered?
  Annals of Surgery, June 20, 2022
• Risk for Asymptomatic Household Transmission of C diff Recently hospitalized individuals may be potential asymptomatic C diff carriers. What is the risk for transmitting this infection to other household members?
  Emerging Infectious Diseases, May 06, 2022
• Overt HE in Cirrhotic Patients With Acute Decompensation This study aimed to determine whether the occurrence of overt hepatic encephalopathy is an independent risk factor for de novo infection in patients with cirrhosis and acute decompensation.
  Alimentary Pharmacology & Therapeutics, April 08, 2022
• Role of Gut Microbiota in HBV Disease Progression and Treatment This review aims to clarify our understanding of the pathophysiology of gut microbiota and their relationship with liver injury in chronic hepatitis B. How might this inform future therapeutics?
  Journal of Viral Hepatitis, February 21, 2022
• Timing of Antibiotic Therapy in the ICU Infections among ICU patients require timely and appropriate antibiotic therapy while also considering the risk of antibiotic resistance.
  Critical Care, December 07, 2021
• Erectile Dysfunction in a Young Man After OTC Omeprazole Was the PPI omeprazole the cause of this young man's sudden erectile dysfunction?
  Journal of Medical Case Reports, September 08, 2021
• Tofacitinib As Salvage Therapy for Refractory Severe UC In a cohort of patients hospitalized with a severe flare of ulcerative colitis, rescue therapy with tofacitinib avoided colectomy in a substantial proportion of cases.
  Alimentary Pharmacology & Therapeutics, August 11, 2021
• Risks, Prevention of C diff Transmission During Transition What strategies might help prevent the transmission of C diff infection after patients are discharged from in-patient settings?
  Emerging Infectious Diseases, July 29, 2021
• Diagnosis and Management of C. Difficile in Patients With IBD Clostridioides difficile infection is a common but serious complication of IBD, and can present atypically. Review the risk factors, diagnosis, and management of CDI in IBD patients in this article.
  Current Opinion in Gastroenterology, June 23, 2021
• Bacterial Mixture vs FMT vs Vancomycin for C. diff Infection Might rectal bacteriotherapy be a safer alternative to fecal microbiota transplantation for recurrent C. difficile infection?
  Alimentary Pharmacology & Therapeutics, May 10, 2021