Oncology News

• ICIs in Melanoma: Predicting Immune-related Adverse Events Melanoma histopathology predicted which patients were most likely to develop immune-related adverse events while taking checkpoint inhibitors.
  Medscape Medical News, December 26, 2023
• The Latest Findings on Major Breast Cancer Trials Here's a roundup of the most recent data from five phase 3 trials presented at SABCS 2023.
  Medscape Medical News, December 21, 2023
• Serum Hormones May Predict AI Benefit for BC Prevention Measuring serum hormone concentrations in postmenopausal women at high risk for developing BC may help identify those most likely to benefit from preventive treatment with an aromatase inhibitor.
  Medscape Medical News, December 21, 2023
• ESD Curbs Adenoma Recurrence but More Adverse Events For large colonic adenomas, endoscopic submucosal dissection reduces the recurrence rate compared with endoscopic mucosal resection, but the adverse event rate is higher.
  Medscape Medical News, December 20, 2023
• New Multiple Myeloma Staging Systems Outperform the Standard Findings from a large US cohort study show comparable accuracy, but better discrimination of patients across disease stages.
  Medscape Medical News, December 19, 2023
• Infection Main Cause of Nonrelapse Death With CAR T Therapy Infections, cardiopulmonary disease, and second cancers were among the leading causes of nonrelapse deaths in patients receiving CAR T-cell therapy, both in clinical trials and clinical practice.
  Medscape Medical News, December 19, 2023
• Where Is the 'Microbiome Revolution' Headed Next? Famed microbiome researcher Dr Martin J. Blaser shares what he sees as the most promising applications, and the rigorous clinical trials needed to realize them.
  Medscape Medical News, December 19, 2023
• GLP-1 RAs Associated With Reduced CRC Risk in T2DM The effects were more profound in patients with overweight and obesity in addition to diabetes.
  Medscape Medical News, December 19, 2023
• Sickle Cell CRISPR Therapy May Offer 'Functional Cure' Patients with severe sickle cell disease could soon be freed from vaso-occlusive crises after receiving an infusion of exa-cel, the first gene-editing therapy to use CRISPR technology.
  Medscape Medical News, December 18, 2023
• Debate Grows Over Facility Fees, Lawmakers Urge Transparency There's continued interest in more transparency about medical costs, in particular facility fees. But there's also a divided opinion about eliminating these payments for US medical care.
  Medscape Medical News, December 18, 2023
• EU Conditional Approval: Gene Editor to Treat Blood Diseases The single-dose therapy involves treating and editing patient stem cells ex vivo, then reinfusing them.
  Medscape Medical News, December 18, 2023
• Alert FDA OKs Enfortumab Vedotin Plus Pembro for Urothelial Cancer The combination is the first approved alternative to first-line chemotherapy.
  Medscape Medical News, December 18, 2023
• Pregnancy Safe After BRCA-Mutated Breast Cancer Although pregnancy after breast cancer is considered safe in general, little data exist for BRCA carriers.
  Medscape Medical News, December 15, 2023
• Top 10 Fictional Docs on Streaming TV Both tried-and-true and out-of-the-ordinary holiday gift ideas are offered to those seeking a great present for a physician.
  Medscape News Slideshows, December 15, 2023
• Belzutifan Approved for Advanced Renal Cell Carcinoma The FDA approval makes belzutifan the first agent specifically indicated for renal cell carcinoma that has progressed after checkpoint inhibition and a VEGF-TKI.
  Medscape Medical News, December 15, 2023
• This Frontline Therapy Is Better in Multiple Myeloma: Study A study directly comparing real-world outcomes suggests patients with transplant-ineligible multiple myeloma do better with frontline triple therapy with daratumumab vs bortezomib.
  Medscape Medical News, December 14, 2023
• Survival-Toxicity Trade-off With T-DM1 in HER+ Breast Cancer Older patients with advanced HER2+ breast cancer do not experience a survival benefit with trastuzumab emtansine vs standard-of-care combination therapy, although toxicity is improved, a trial shows.
  Medscape Medical News, December 14, 2023
• Alert Antiparasitic Wins FDA Approval for High-Risk Neuroblastoma The FDA approved eflornithine to treat this rare cancer in adult and pediatric patients. The drug has also been approved to reduce excessive facial hair growth and to treat sleeping sickness.
  Medscape Medical News, December 14, 2023
• What if a Single GLP-1 Shot Could Last for Months? New hydrogel technology could reduce GLP-1 injections from daily or weekly to three times a year.
  Medscape Medical News, December 14, 2023
• SCD Mortality Rates Improved for Black Patients in 2010s The average age of death for Black US patients with sickle cell disease rose from 39 years in 1999-2009 to 43 years in 2010-2020, reflecting improvements in treatment.
  MDedge News, December 14, 2023
• Less Is More for Axillary Surgery in Early Breast Cancer Women with early breast cancer can safely undergo less extensive axillary surgery because it has no impact on recurrence or mortality rates but reduces the risk for lymphedema, a meta-analysis shows.
  Medscape Medical News, December 13, 2023
• ASH 2023 ASH 2023: Equity, Sickle Cell, and Real-Life Outcomes Health equity, sickle cell disease, and the thoughtful use of artificial intelligence and social media are among the key themes to be presented at the annual meeting of the American Society of Hematology.
  MDedge News, December 04, 2023
• How the Microbiome Influences the Success of Cancer Therapy Microbial diversity affects whether a tumor grows, leads to inflammation, develops immune escape mechanisms, or develops therapeutic resistance, said an internal medicine specialist.
  Medscape Medical News, December 04, 2023
• MSWS 2023 New Tools Available to Help Diagnose Skin Cancer Emerging technologies aim to improve skin cancer diagnosis without biopsies.
  Medscape Medical News, December 03, 2023
• MSWS 2023 Misdiagnoses Among Challenges in Managing Cutaneous Lymphoma Although predictive tools to identify those at risk of disease progression are in their infancy, the development of such tools is crucial for improving patient outcomes.
  Medscape Medical News, December 02, 2023
• What Is the Dark Side of GLP-1 Receptor Agonists? Doctors who prescribe this class of medication should be aware of the rare side effects with which it is associated, said an obesity expert.
  Medscape Medical News, December 01, 2023
• SABCS 2023 SABCS 2023 Highlights Breast Cancer De-Escalation From humble beginnings in 1977, 10,000 people are expected to attend this year's breast cancer meeting in San Antonio.
  Medscape Medical News, December 01, 2023
• ASCO Details How to Manage Ongoing Cancer Drug Shortage The guidance also recommends counseling to help patients and providers who are struggling with 'psychological or moral distress' from ongoing shortages.
  Medscape Medical News, November 30, 2023
• Pancreatic Cystic Neoplasms Rarely Turn Cancerous Individuals with intraductal papillary mucinous neoplasms that lack 'worrisome or high-risk features' have no greater risk of pancreatic cancer than individuals without IPMNs.
  MDedge News, November 30, 2023
• Small-Volume Bloodwork Tubes May Reduce Transfusions in ICUs Decreasing blood supply use could also preserve blood products for patients undergoing cancer treatment or surgery and for those with trauma or other illnesses.
  Medscape Medical News, November 30, 2023
• Avoid Anti-HER2 Cancer Therapies During Pregnancy Women with HER2-positive breast cancer who receive HER2-targeted therapies during pregnancy face a higher risk for severe adverse outcomes to their fetus or newborn, new research indicates.
  Medscape Medical News, November 29, 2023
• MRIs, MRI-Guided Biopsies Detect Prostate Cancer Affordably Standard biopsies sometimes fail to detect prostate cancer or produce false positives. MRI plus MRI-guided biopsies not only produce more accurate results but carry a fair price tag, researchers said.
  Medscape Medical News, November 29, 2023
• Alert FDA Investigates Secondary Cancers From CAR T-Cell Therapies The FDA has determined that the risk for lymphoma and other T-cell cancers may apply to approved BCMA- and CD-19–directed CAR T-cell immunotherapies.
  Medscape Medical News, November 28, 2023
• Alert FDA OKs New Agent to Block Chemotherapy-Induced Neutropenia The new colony-stimulating factor from China proved comparable to pegfilgrastim (Neulasta) in clinical testing.
  Medscape Medical News, November 28, 2023
• ASTRO Updates on Partial Breast Irradiation in Early Cancer The new guideline replaces 2017 guidance after new evidence from multiple large trials emerged, indicating comparable outcomes with partial and whole breast radiation.
  Medscape Medical News, November 28, 2023
• Long-Term Organ Preservation in Rectal Cancer Is Possible Long-term data from the OPRA trial show organ preservation at 5 years in about half of patients with stage II/III rectal adenocarcinoma who received total neoadjuvant therapy.
  Medscape Medical News, November 28, 2023
• AANEM 2023 Novel Myasthenia Gravis Therapies Bring Opportunities New treatments for myasthenia gravis are bringing new promise to patients, but their use must be balanced against short-term and long-term risks.
  MDedge News, November 27, 2023
• Alert FDA Approves Nirogacestat for Desmoid Tumors This is the first drug approved to treat desmoid tumors.
  Medscape Medical News, November 27, 2023
• Grail Gets FDA OK for Study of Cancer Blood Test Grail announced a step that may help move the company closer to securing Medicare reimbursement for its Galleri multicancer blood test, sold in the US since 2021.
  Medscape Medical News, November 27, 2023
• White House Appoints New NCI Director After years of working with the National Cancer Institute, W. Kimryn Rathmell, MD, PhD, gets the call to run the institute.
  Medscape Medical News, November 22, 2023