Endocrine Society News

 
 
  • GLP-1s, Antidiabetic Medications Show Safety in Pregnancy New research shows use of the drugs in pregnancy is on the rise, particularly in the United States, and although teratogenic risks appear low, limitations are notable.
  • Postmenopausal Testosterone for Low Libido Only, Doctors Say Can testosterone replacement therapy help postmenopausal patients restore libido and improve overall health and vitality?
  • Support Tool Reduces Hypoglycemia Risk in Type 2 Diabetes Shared decision making using a novel clinical-decision support tool led to a reduced risk for hypoglycemic events in a prospective study of 94 high-risk elderly people with type 2 diabetes.
  • Ketogenic Diet Short-Term May Benefit Women With PCOS Meta-analysis showed improvements in reproductive hormone levels and weight loss.
  • ENDO 2023 Early Time-Restricted Feeding Dampens Blood Glucose Peaks Limiting food intake to an 8 AM-4 PM window significantly reduced the mean amplitude of glycemic excursions by about 9 mg/dL in a cross-over study of 10 adults with prediabetes.
  • ENDO 2023 CGM Alarm Fatigue in Youth? Teenagers often set the alarms on their continuous glucose monitors to levels that cause needless distress, researchers found.
  • ENDO 2023 Surgery, Radioactive Iodine for Hyperthyroidism Up Survival In large cohort study, both radioactive iodine and thyroidectomy extended longevity compared with antithyroid medications, while surgery raised the risk for weight gain.
  • ENDO 2023 Athletes With Type 1 Diabetes Ignore Hypoglycemia Warnings Survey results from 102 US adults with type 1 diabetes who exercise often showed concerning high rates of behaviors that run counter to expert recommendations and put patients at risk of hypoglycemia.
  • ENDO 2023 Surge in Desiccated Thyroid Extract Use for Hypothyroidism Prescriptions for desiccated thyroid hormone for newly diagnosed hypothyroidism nearly doubled, while scripts for first-line levothyroxine monotherapy dropped, to the surprise of the researchers.
  • ENDO 2023 A 'One-Stop Shop': New Guidance on Hormones and Aging The 40-page statement covers natural history, available therapies, clinical trial data, key points, and gaps in the research, and is described by one expert as a 'one-stop shop' for information.
  • ENDO 2023 BMI 'Vastly Underestimates' True Obesity Body mass index missed half of US adults with obesity identified by body fat percentage in DEXA scans, strengthening the case that obesity assessment must be based on more than BMI alone.
  • ENDO 2023 Anabolic-Steroid Withdrawal Regimens Show Promise in Men Researchers study men taking illegal self-treatments bought online to help them tackle side effects experienced when they stop taking anabolic steroids. The former seem to work to restore hormone levels.
  • ENDO 2023 Big Trial Reassures on Heart Safety of Testosterone in Men 'Real data on something that we've been prescribing for decades,' is how one expert describes the results of the FDA-mandated TRAVERSE trial of testosterone gel versus placebo in men with hypogonadism.
  • ENDO 2023 Vitamin D Deficiency: Can We Improve Diagnosis? Researchers propose the use of ratios of vitamin D metabolites that take into account individual differences in vitamin D binding proteins to improve prediction of secondary hyperparathyroidism risk.
  • Predicting Hypothyroid Onset in Adults With Kidney Disease Researchers derived and validated a prediction model for incident hypothyroidism in adults with stage 4-5 chronic kidney disease with an eGFR of less than 30 mL/min/1.73m2.
  • Alert Once-Weekly Growth Hormone Somapacitan Approved for Kids Somapacitan (Sogroya, Novo Nordisk) injections are indicated to replace endogenous growth hormone in children with growth hormone deficiency.
  • Thyroid Dysfunction Mild With Cancer Immunotherapy In a real-world study, the prevalence of immune checkpoint inhibitor–associated thyroid dysfunction was greater than 50%, but cases were mild and were even linked to better survival.
  • Could Vitamin D Supplementation Help in Long COVID? If confirmed in large randomized clinical trials, vitamin D supplementation could be a strategy to reduce the burden of long COVID, say researchers, as suggested by a new retrospective study.
  • Alert FDA OKs New Drug for Hot Flashes The first-in-class approval of fezolinetant (Veozah) is for treatment of moderate to severe vasomotor symptoms associated with menopause.
  • AACE 2023 New AACE Statement Tries to Fight Weight Bias and Stigma The proposed new staging for 'adiposity-based chronic disease,' incorporates the experience of weight-based stigma and bias in an attempt to break the 'vicious cycle,' says the lead author.
  • Lifestyle Med Experts Tell How to Deprescribe Diabetes Meds Recently published account details the medication de-escalation methods used by lifestyle medicine providers when patients show a decreased need for diabetes medications.