Cutaneous Metastasis as a First Presentation of Lung Carcinoma

A Case Series

Saida Sakhri; Ines Zemni; Mohamed Ali Ayadi; Lamia Naija; Nadia Boujelbene; Tarek Ben Dhiab

Disclosures

J Med Case Reports. 2023;17(315) 

In This Article

Abstract and Introduction

Abstract

Introduction: Cutaneous metastases (CM) revealing lung carcinoma are extremely rare, accounting for 0.8%. The diagnosis is guided by histology and immunohistochemistry. Treatment is palliative. The prognosis is poor.

Case Presentation: This is a retrospective study of the available clinical and histological records of four North African patients with CM revealing lung cancer treated at our institute between 2004 and 2010. Three men and one woman were registered. The mean age was 54.5 years (38–74 years). Two patients had primary adenocarcinoma, one patient had small cell carcinoma and one had squamous cell carcinoma. Treatment was based on chemotherapy in two cases and antalgic radiotherapy in two cases, one patient underwent surgical resection as the lesion was infected. The overall survival after diagnosis was between one and four months.

Conclusions: A skin nodule can be the first symptom revealing lung cancer. A rare clinical presentation that should not be taken for a benign nodule, the biopsy and histological study with immunohistochemistry confirm the diagnosis.

Introduction

Cutaneous metastasis (CM) from primary visceral malignancy is an uncommon entity. The incidence is between 1 and 12%. skin metastasis from lung carcinoma account for 3.4%. Generally it occurs at the terminal stage of the disease, but it may rarely reveal the illness in 0.8%.[1,2] We aim to report our experience and discuss diagnoses and therapeutic management with a review of the literature.

processing....