Advanced and Metastatic Breast Cancer: A Shift in Thinking

Sara M. Tolaney, MD, MPH

Disclosures

January 06, 2023

Sara M. Tolaney, MD, MPH, considers the dramatic advances in the treatment of advanced and metastatic breast cancer that have arisen in recent years, advances that represent an exponential increase over previous decades.

Dr Tolaney underscores the point that newer, targeted approaches operate in both a specific form, in which mutation drivers are directly addressed, and in a more general form, in which various protein markers allow the precise delivery of chemotherapeutic agents. Together, these two approaches reflect the rich rewards of the latest research in oncology and represent an evolution from earlier, limited therapeutic horizons toward more expansive modes of therapy.

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