From theheart.org on Medscape

Coverage from the

American Heart Association (AHA) Scientific Sessions 2021

November 13 - 15, 2021; Virtual

November 13 - 15, 2021 Virtual

AHA 2021 Obicetrapib: CETP Inhibitor Impresses in LDL Lowering A new lipid-lowering agent in a class that had been written off by many is being developed by a group of academic experts, with new data showing large LDL reductions on top of high-intensity statins.
Medscape Medical News, November 24, 2021
AHA 2021 Daily Oral PCSK9 Inhibitor Encouraging in Phase 1 Trials What if the cholesterol-crushing efficacy of current PCSK9 inhibitors came in a pill instead of a syringe? That's one possibility for a Merck agent in the earliest stages of human trials.
Medscape Medical News, November 23, 2021
AHA 2021 ACEI, ARBs in COVID-19: Be Aware of Acute Kidney Injury The largest randomized dataset yet of ACE inhibitors and angiotensin receptor blockers in COVID-19 shows reassuring results, but with a potential new link to kidney injury in hospitalized patients.
Medscape Medical News, November 22, 2021

Meeting Highlights At A Glance

AHA 2021 Highlights: Surgery and Drugs Studies on early valvular heart surgery and SGLT2 inhibitors in acute heart failure are the featured highlights from AHA 2021.
AHA 2021 Highlights: Patient Centric Among the highlights: a strategy to lower blood pressure in rural communities, and studies on how coffee and alcohol affect heart rhythm.

Conference News

AHA 2021 New AKI Risk Score for PCI Patients Passes Validation
Medscape Medical News, December 7, 2021
AHA 2021 SGLT2 Inhibitor Use Tied to Fewer Atrial Arrhythmias
Medscape Medical News, December 2, 2021
AHA 2021 Pandemic Lockdowns, Cleaner Air Tied to Reduced MIs
Medscape Medical News, November 29, 2021
AHA 2021 Prehospital Copeptin Test Helps to Quickly Rule Out MI
Medscape Medical News, November 29, 2021
AHA 2021 Remote Non-Physician Care Helps BP, LDL Control
Medscape Medical News, November 29, 2021
AHA 2021 Anticoagulants Can Ease Cognitive Decline in AF Patients
Medscape Medical News, November 25, 2021
AHA 2021 Obicetrapib: CETP Inhibitor Impresses in LDL Lowering
Medscape Medical News, November 24, 2021
AHA 2021 Sacubitril/Valsartan May Alter Trajectory of Preclinical HFpEF
Medscape Medical News, November 23, 2021
AHA 2021 Daily Oral PCSK9 Inhibitor Encouraging in Phase 1 Trials
Medscape Medical News, November 23, 2021
AHA 2021 ACEI, ARBs in COVID-19: Be Aware of Acute Kidney Injury
Medscape Medical News, November 22, 2021
AHA 2021 Penicillin Slows Latent Rheumatic Heart Disease Progression
Medscape Medical News, November 22, 2021
AHA 2021 Fewer Strokes on Myosin Activator in HFrEF: GALACTIC-HF
Medscape Medical News, November 19, 2021
AHA 2021 Fire Fighters' Blood Pressure Surges When Called to Action
Medscape Medical News, November 19, 2021
AHA 2021 Atrial Fibrillation Risk Climbs in First Year of Breast Cancer
Medscape Medical News, November 19, 2021
AHA 2021 Ticagrelor Reversal Agent Achieves Quick Hemostasis: REVERSE-IT
Medscape Medical News, November 18, 2021
AHA 2021 EMPEROR-Preserved Findings Confirmed in 'True' HFpEF Patients
Medscape Medical News, November 18, 2021
AHA 2021 Left-Main PCI, CABG Mortality Similar; Choice Remains Complex
Medscape Medical News, November 17, 2021
AHA 2021 ASCEND: Hint of Dementia Protection With Aspirin in T2D
Medscape Medical News, November 17, 2021
AHA 2021 Canagliflozin Improves HF Symptoms in Fully Remote Trial
Medscape Medical News, November 16, 2021
AHA 2021 No Benefit of Antiplatelets in Noncritical COVID: ACTIV-4a
Medscape Medical News, November 16, 2021

AHA 2021 Negative Stem Cell Results in HF May Still Have Promise: DREAM-HF
Medscape Medical News, November 16, 2021
AHA 2021 Empagliflozin Wins in Tough Stabilized Acute-HF Setting
Medscape Medical News, November 16, 2021
AHA 2021 EHR Alerts Have No Impact on Inpatient HF Treatment or Outcomes
Medscape Medical News, November 15, 2021
AHA 2021 Oral Factor XIa Inhibitor Cuts Post-Op VTE Risk: AXIOMATIC-TKR
Medscape Medical News, November 15, 2021
AHA 2021 High-Dose Fish Oil: "Intriguing" Results in COVID-19
Medscape Medical News, November 15, 2021
AHA 2021 No Advantage for LAA Ligation With Pulmonary Vein Isolation
Medscape Medical News, November 15, 2021
AHA 2021 Finerenone, Sotagliflozin Benefit HF Despite Renal Dysfunction
Medscape Medical News, November 15, 2021
AHA 2021 BP Control Rates Dropped During Pandemic: BP Track
Medscape Medical News, November 14, 2021
AHA 2021 Alcoholic Drinks Stand Out in Novel Trial Exploring AF Triggers
Medscape Medical News, November 14, 2021
AHA 2021 Fitbit Algorithm Successfully Detects AF
Medscape Medical News, November 14, 2021
AHA 2021 CRAVE: No Spike in Atrial Arrhythmias Among Coffee Drinkers
Medscape Medical News, November 14, 2021
AHA 2021 Earlier Epinephrine in Cardiac Arrest Tied to Better Outcomes
Medscape Medical News, November 14, 2021
AHA 2021 Procedure Reduces Postop AF After Cardiac Surgery: PALACS
Medscape Medical News, November 14, 2021
AHA 2021 Village Health Workers Successfully Treat Hypertension
Medscape Medical News, November 13, 2021
AHA 2021 Early SAVR Tops Watchful Waiting in Severe No-Symptom AS: AVATAR
Medscape Medical News, November 13, 2021
AHA 2021 VEST: External Sheath for CABG Vein Grafts Shows Promise
Medscape Medical News, November 13, 2021
AHA 2021 Vegetable Fats Tied to Lower Stroke Risk Than Animal Fat
Medscape Medical News, November 13, 2021
AHA 2021 Concomitant Tricuspid-Mitral Surgery Beneficial but With a Tradeoff
Medscape Medical News, November 13, 2021
AHA 2021 CABG Safe 3 Days After Stopping Ticagrelor: RAPID CABG
Medscape Medical News, November 13, 2021
AHA 2021 AHA 2021 Puts Scientific Dialogue, Health Equity Center Stage
Medscape Medical News, November 8, 2021

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Perspectives

Booze Out, Coffee Okay to Outsmart Atrial Fibrillation?
Interviewer: Jagmeet P. Singh, MD, MSc;
Interviewee: Gregory M. Marcus, MD, MAS
CHIEF-HF: No-Touch Initiation of Canagliflozin Improves QoL
Ileana L. Piña, MD, MPH; Eldrin F. Lewis, MD, MPH
Lessons on AF Detection From the Fitbit Heart Study
Jagmeet P. Singh, MD, MSc; Steven A. Lubitz, MD, MPH
PCI vs CABG for Left Main CAD: A Never-Ending Debate?
John Mandrola, MD
Surgical Consult From AHA: Act Earlier in AS and TR?
Michelle L. O'Donoghue, MD; Patrick T. O'Gara, MD
Early Surgery in Asymptomatic AS Should Wait
John Mandrola, MD
Questions Remain on Tricuspid Repair at Time of Mitral Surgery
John Mandrola, MD
Mandrola Previews the Virtual AHA 2021
John Mandrola, MD

News from AHA 2020

SAMSON Pins Most Muscle Pain With Statins on the Nocebo Effect Some patients really do get side effects, such as muscle pain, from statins, but the trial suggests that '90% of this symptomatic burden is elicited by placebo tablets too,' researchers say.
Medscape Medical News, Nov 15, 2020
STRENGTH Trial Questions CV Benefit of High-Dose Omega-3s Questions about the CV benefit of omega-3 fatty acids and the high-dose eicosapentaenoic acid product, Vascepa, have resurfaced with results of the STRENGTH trial using a combination product, Epanova.
Medscape Medical News, Nov 15, 2020
SGLT1/2 Inhibitor Shows 'Spectacular' Safety, Efficacy in T2D Sotagliflozin, a novel type of sodium-glucose cotransporter inhibitor, showed the diverse benefits this drug class provides along with some new twists in a pair of international pivotal trials.
Medscape Medical News, Nov 18, 2020
Combined OCT, Cardiac MRI Unravels Root Cause in Most MINOCA The multimodal imaging strategy has the potential to provide reassurance and clarity for women who present with an MI without a major artery blockage, who are often left without a definitive diagnosis.
Medscape Medical News, Nov 14, 2020

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